Catherine Caillaud Selected Research

Hexosaminidases (Hexosaminidase)

1/2020	Natural History of Adult Patients with GM2 Gangliosidosis.
1/2018	Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice.
8/2014	Chaperone therapy for GM2 gangliosidosis: effects of pyrimethamine on β-hexosaminidase activity in Sandhoff fibroblasts.
1/2013	Characterization of seven novel mutations on the HEXB gene in French Sandhoff patients.
3/2010	Induced secretion of beta-hexosaminidase by human brain endothelial cells: a novel approach in Sandhoff disease?
3/2006	Reversion of the biochemical defects in murine embryonic Sandhoff neurons using a bicistronic lentiviral vector encoding hexosaminidase alpha and beta.
11/2005	Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Catherine Caillaud Research Topics

Disease

13	Glycogen Storage Disease Type II (Pompe's Disease) 01/2019 - 09/2003
11	Gaucher Disease (Gaucher's Disease) 01/2019 - 01/2002
7	Sandhoff Disease (Sandhoff's Disease) 01/2020 - 11/2005
5	Fabry Disease (Fabry's Disease) 01/2020 - 05/2008
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 11/2005
4	Respiratory Insufficiency (Respiratory Failure) 02/2010 - 11/2008
4	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 02/2010 - 11/2008
3	Mucopolysaccharidosis IV (Morquio Syndrome) 01/2022 - 08/2009
3	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2020 - 04/2009
2	Mucopolysaccharidoses 01/2022 - 03/2012
2	Seizures (Absence Seizure) 11/2021 - 01/2020
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020 - 01/2013
2	Tay-Sachs Disease 01/2020 - 02/2010
2	GM2 Gangliosidoses (GM2 Gangliosidosis) 01/2020 - 08/2014
2	Apnea 01/2019 - 12/2015
2	Obstructive Sleep Apnea 01/2019 - 12/2015
2	Muscular Diseases (Myopathy) 11/2016 - 11/2011
2	Mucopolysaccharidosis I (Hurler Syndrome) 12/2015 - 07/2004
1	Microcephaly 11/2021
1	Fatigue 07/2020
1	Proteinuria 01/2020
1	Cerebellar Ataxia (Dysmetria) 01/2020
1	Frontotemporal Dementia (Semantic Dementia) 01/2020
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020
1	Cognitive Dysfunction 01/2020
1	Hereditary Spastic Paraplegia 01/2018
1	Ciliopathies 10/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 08/2014
1	Sphingolipidoses (Sphingolipidosis) 08/2014
1	Vacuolar myopathy 06/2013
1	Parkinson Disease (Parkinson's Disease) 10/2012
1	Spontaneous Fractures (Pathological Fracture) 10/2012
1	Osteonecrosis (Kienbock's Disease) 10/2012
1	Infarction (Infarctions) 10/2012
1	Cardiomegaly (Heart Hypertrophy) 02/2010
1	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 01/2010
1	Protein Deficiency 01/2010
1	GM1 Gangliosidosis (Gangliosidosis GM1) 08/2009
1	Dysostoses 08/2009
1	Bone Resorption 01/2002

Drug/Important Bio-Agent (IBA)

12	EnzymesIBA 01/2019 - 01/2002
11	AcidsIBA 11/2018 - 11/2008
9	GlycogenIBA 06/2013 - 09/2003
7	Hexosaminidases (Hexosaminidase)IBA 01/2020 - 11/2005
7	Glucosylceramidase (Glucocerebrosidase)IBA 01/2019 - 01/2002
6	alpha-Glucosidases (Acid Maltase)IBA 11/2011 - 11/2008
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2010
5	G(M2) Ganglioside (Ganglioside GM2)IBA 08/2014 - 11/2005
4	GlucosidasesIBA 11/2018 - 11/2011
3	alpha-Galactosidase (Beano)IBA 01/2020 - 05/2008
3	Mannose (D-Mannose)IBA 01/2019 - 11/2016
2	GalactosidasesIBA 01/2022 - 03/2012
2	imiglucerase FDA Link 01/2019 - 05/2009
2	Pharmaceutical PreparationsIBA 01/2018 - 11/2016
2	AntibodiesIBA 01/2018 - 11/2016
2	SphingolipidsIBA 08/2014 - 01/2010
2	Biomarkers (Surrogate Marker)IBA 06/2014 - 01/2002
2	SulfatasesIBA 03/2012 - 08/2010
2	beta-N-AcetylhexosaminidasesIBA 03/2010 - 02/2010
2	Hexosaminidase A (Hex A)IBA 02/2010 - 03/2006
1	Retinaldehyde (Retinal)IBA 11/2021
1	chitotriosidaseIBA 07/2020
1	Hemoglobins (Hemoglobin)IBA 07/2020
1	Immunoglobulin A (IgA)IBA 01/2020
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2020
1	GlycosphingolipidsIBA 01/2020
1	ProgranulinsIBA 01/2020
1	GangliosidesIBA 01/2018
1	human GAA protein (Myozyme)FDA Link 11/2016
1	Oxygen (Dioxygen)IBA 12/2015
1	Pyrimethamine (Daraprim)FDA Link 08/2014
1	Creatine Kinase (Creatine Phosphokinase)IBA 06/2013
1	Glycogen Synthase (Synthase I)IBA 01/2011
1	Protein Isoforms (Isoforms)IBA 01/2011
1	ArylsulfatasesIBA 08/2010
1	beta-Hexosaminidase beta ChainIBA 03/2010
1	hydroxide ionIBA 03/2010
1	Cerebroside-Sulfatase (Arylsulfatase A)IBA 01/2010
1	Sulfoglycosphingolipids (Sulfatides)IBA 01/2010
1	acid beta-galactosidaseIBA 08/2009
1	beta-Galactosidase (Lactaid)IBA 08/2009
1	LigandsIBA 04/2009
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2009
1	Fas Ligand Protein (Fas Ligand)IBA 04/2009
1	globotriaosylceramide (globotriosylceramide)IBA 05/2008
1	Adenosine Triphosphatases (ATPase)IBA 03/2006
1	Dermatan SulfateIBA 07/2004
1	Iduronidase (alpha-L-Iduronidase)IBA 07/2004
1	GlycolipidsIBA 09/2002
1	OsteocalcinIBA 01/2002
1	Collagen Type I (Type I Collagen)IBA 01/2002
1	Glucosylceramides (Glucocerebrosides)IBA 01/2002

Therapy/Procedure

8	Enzyme Replacement Therapy 01/2019 - 06/2008
6	Therapeutics 10/2018 - 05/2009
1	Enzyme Therapy 01/2019
1	Continuous Positive Airway Pressure 01/2019
1	Intravenous Administration 01/2018
1	Hematopoietic Stem Cell Transplantation 12/2015
1	Splenectomy 10/2012